(ANL) Adlai Nortye American - Ratings and Ratios

Exchange: NASDAQ • Country: Cayman Islands • Currency: USD • Type: Common Stock •

ANL: Cancer, Therapies, Inhibitors, Antagonist, Degrader

Adlai Nortye Ltd. (NASDAQ:ANL) is a clinical-stage biotechnology company specializing in the development of innovative cancer therapies. The company operates primarily in the U.S. and Mainland China, focusing on addressing unmet medical needs in oncology. Its lead candidate, AN2025, is a pan-phosphoinositide 3-kinase (PI3K) inhibitor currently in Phase III clinical trials for the treatment of recurrent or metastatic head and neck squamous cell carcinomas (HNSCC). This trial aims to evaluate the efficacy and safety of AN2025 in patients with limited treatment options.

Adlai Nortye is also advancing AN0025, a small molecule prostaglandin E receptor 4 (EP4) antagonist designed to modulate the tumor microenvironment. AN0025 is in Phase Ib clinical trials for multiple indications, including recurrent non-small cell lung cancer (NSCLC) and urothelial cancer after anti-PD-1/PD-L1 treatments, as well as recurrent triple-negative breast cancer (TNBC), microsatellite stable (MSS) colorectal cancer, and cervical cancer. Additionally, AN4005, an oral small-molecule PD-L1 inhibitor, is in Phase I clinical trials. This compound works by inducing and stabilizing PD-L1 dimerization, thereby disrupting the PD-1/PD-L1 interaction, a key mechanism in cancer immunotherapy.

The company’s preclinical pipeline includes AN8025, a multifunctional antibody designed to modulate both T cells and antigen-presenting cells (APCs); AN1025, an oral small molecule targeting ß-catenin for degradation; and AN9025, an oral small molecule pan-KRAS inhibitor. These candidates highlight Adlai Nortye’s commitment to targeting pathways critical to cancer progression and immune evasion. Founded in 2004 and headquartered in Grand Cayman, the Cayman Islands, the company has established a robust pipeline focused on next-generation cancer therapies.

From a technical perspective, ANL stock is currently trading at $2.20, with a 20-day simple moving average (SMA) of $2.18 and a 50-day SMA of $2.15. The 200-day SMA stands at $3.15, indicating a recent downtrend. The average true range (ATR) of 0.19 reflects moderate volatility. Over the next three months, the stock is likely to face resistance at $2.50, with potential support at $2.00. The low average volume of 7,010 shares suggests limited liquidity, which could amplify price movements.

Fundamentally, Adlai Nortye has a market capitalization of $114.76 million, with a price-to-book (P/B) ratio of 1.52, indicating investor confidence in its asset value. The price-to-sales (P/S) ratio of 16.68 reflects expectations of significant future revenue growth. However, the absence of a trailing P/E ratio underscores the company’s current focus on research and development over profitability. With a robust pipeline and ongoing clinical trials, Adlai Nortye’s stock is likely to remain sensitive to clinical trial outcomes and broader market sentiment toward biotechnology stocks.

Over the next three months, Adlai Nortye’s stock is expected to remain volatile, driven by technical resistance levels and the company’s progress in its clinical trials. Investors should monitor updates on the Phase III trial for AN2025, as well as any developments in the earlier-stage pipeline, which could act as catalysts for price movement. The stock’s low trading volume may exacerbate swings in response to news, making it a higher-risk investment in the short term.

Additional Sources for ANL Stock

ANL Stock Overview

Market Cap in USD 115m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2023-09-29

ANL Stock Ratings

Growth 5y -52.8%
Fundamental 10.4%
Dividend 0.0%
Rel. Strength Industry -73.8
Analysts 4/5
Fair Price Momentum 1.42 USD
Fair Price DCF -

ANL Dividends

No Dividends Paid

ANL Growth Ratios

Growth Correlation 3m 22.4%
Growth Correlation 12m -79.3%
Growth Correlation 5y -82.2%
CAGR 5y -72.77%
CAGR/Max DD 5y -0.83
Sharpe Ratio 12m -0.04
Alpha -95.30
Beta 1.98
Volatility 79.23%
Current Volume 6.1k
Average Volume 20d 6.1k
What is the price of ANL stocks?
As of March 18, 2025, the stock is trading at USD 2.25 with a total of 6,130 shares traded.
Over the past week, the price has changed by -3.43%, over one month by +2.27%, over three months by +0.00% and over the past year by -75.07%.
Is Adlai Nortye American a good stock to buy?
Neither. Based on ValueRay Fundamental Analyses, Adlai Nortye American is currently (March 2025) neither a good nor a bad stock to buy. It has a ValueRay Fundamental Rating of 10.36 and therefor a neutral outlook according to the companies health.
Based on ValueRays Analyses, Dividends and Discounted-Cash-Flow, the Fair Value of ANL as of March 2025 is 1.42. This means that ANL is currently overvalued and has a potential downside of -36.89%.
Is ANL a buy, sell or hold?
Adlai Nortye American has received a consensus analysts rating of 4.00. Therefor, it is recommend to buy ANL.
  • Strong Buy: 0
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0
What are the forecast for ANL stock price target?
According to ValueRays Forecast Model, ANL Adlai Nortye American will be worth about 1.7 in March 2026. The stock is currently trading at 2.25. This means that the stock has a potential downside of -25.78%.
Issuer Forecast Upside
Wallstreet Target Price 9 300%
Analysts Target Price 9 300%
ValueRay Target Price 1.7 -25.8%