EXEL Stock Analysis: Exelixis | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 12.540m USD | 12M Return: 33.2% | US30161Q1040 | Charts, Fundamentals & Technical Analysis

Cabometyx, Cometriq, Cotellic, Minnebro
Total Rating 66
Safety 90
Buy Signal -0.16
Biotechnology
Industry Rotation: -14.4
Market Cap: 12.5B
Avg Turnover: 140M
Risk 3d forecast
Volatility36.8%
VaR 5th Pctl5.28%
VaR vs Median-9.39%
Reward TTM
Sharpe Ratio0.86
Rel. Str. IBD56.5
Rel. Str. Peer Group32.3
Character TTM
Beta0.913
Beta Downside0.199
Hurst Exponent0.345
Drawdowns 3y
Max DD25.34%
CAGR/Max DD1.37
CAGR/Mean DD5.28
EPS (Earnings per Share) EPS (Earnings per Share) of EXEL over the last years for every Quarter: "2021-06": 0.37, "2021-09": 0.2, "2021-12": 0.35, "2022-03": 0.26, "2022-06": 0.28, "2022-09": 0.31, "2022-12": -0.03, "2023-03": 0.16, "2023-06": 0.31, "2023-09": 0.1, "2023-12": 0.33, "2024-03": 0.17, "2024-06": 0.84, "2024-09": 0.47, "2024-12": 0.55, "2025-03": 0.62, "2025-06": 0.75, "2025-09": 0.78, "2025-12": 0.94, "2026-03": 0.87, "2026-06": 0.82,
EPS CAGR: 87.14%
EPS Trend: 95.0%
Last SUE: 0.50
Qual. Beats: 0
Revenue Revenue of EXEL over the last years for every Quarter: 2021-06: 385.177, 2021-09: 328.423, 2021-12: 451.14, 2022-03: 355.98, 2022-06: 419.427, 2022-09: 411.738, 2022-12: 423.917, 2023-03: 408.788, 2023-06: 469.848, 2023-09: 471.92, 2023-12: 479.652, 2024-03: 425.226, 2024-06: 637.178, 2024-09: 539.542, 2024-12: 566.755, 2025-03: 555.447, 2025-06: 568.261, 2025-09: 597.755, 2025-12: 598.663, 2026-03: 610.812, 2026-06: 628.69,
Rev. CAGR: 12.36%
Rev. Trend: 96.3%
Last SUE: -0.03
Qual. Beats: 0

Warnings

Below Avwap Earnings

Tailwinds

No distinct edge detected

Seasonality 11.6 years of data

Jan -1.4% 19
Feb +0.1% 7
Mar +4.9% 8
Apr -1.8% 8
May +0.3% 7
Jun +2.8% 19
Jul -2.0% 19
Aug -0.3% 0
Sep -3.0% 14
Oct -7.9% 40
Nov +5.2% 42
Dec +2.5% 12

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: EXEL Exelixis

Exelixis, Inc. is a U.S.-based oncology company that discovers, develops, and commercializes new medicines for difficult-to-treat cancers. Its marketed portfolio is anchored by cabozantinib, the active ingredient in both CABOMETYX (advanced renal cell carcinoma) and COMETRIQ (metastatic medullary thyroid cancer), and also includes COTELLIC, a MEK inhibitor used in combination therapy for advanced melanoma. Beyond oncology, the company markets MINNEBRO, an oral mineralocorticoid receptor blocker approved for hypertension in Japan through a regional partner.

The company is advancing a pipeline of experimental oncology candidates, including kinase inhibitors (zanzalintinib), a USP1 inhibitor for BRCA-mutated tumors (XL309), and several antibody-drug conjugates and bispecific antibodies (XB010, XB628, XB371). Exelixis supplements its internal R&D with an extensive network of research collaborations and license agreements with major pharmaceutical and biotechnology partners, including Ipsen, Takeda, Roche/Genentech, Bristol-Myers Squibb, and Daiichi Sankyo-a licensing-heavy model common among biotech firms seeking to extend geographic reach and share development risk. Incorporated in 1994 and headquartered in Alameda, California, Exelixis operates within the biotechnology sub-industry of the broader health care sector.

Headlines to Watch Out For
  • CABOMETYX sales growth drives revenue and label expansions
  • Zanzalintinib and ADC pipeline catalysts advance through clinical trials
  • Ipsen Takeda partnerships deliver ex-US royalty revenue
Piotroski VR-10 (Strict) 6.5
Net Income: 860.6m TTM > 0 and > 6% of Revenue
FCF/TA: 0.47 > 0.02 and ΔFCF/TA 20.35 > 1.0
NWC/Revenue: 36.49% < 20% (prev 37.88%; Δ -1.39% < -1%)
CFO/TA 0.47 > 3% & CFO 1.18b > Net Income 860.6m
Net Debt (-673.5m) to EBITDA (999.8m): -0.67 < 3
Current Ratio: 3.46 > 1.5 & < 3
Outstanding Shares: last quarter (259.7m) vs 12m ago -8.69% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 94.19% > 50% (prev 83.27%; Δ 10.92% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBIT TTM and Interest Expense TTM)
Altman Z'' 7.50
A: 0.36 (Total Current Assets 1.25b - Total Current Liabilities 361.9m) / Total Assets 2.49b
B: -0.11 (Retained Earnings -262.5m / Total Assets 2.49b)
C: 0.38 (EBIT TTM 971.5m / Avg Total Assets 2.59b)
D: 2.83 (Book Value of Equity 1.84b / Total Liabilities 650.5m)
Altman-Z'' = 7.50 = AAA
Beneish M -2.99
DSRI: 1.05 (Receivables 334.6m/292.4m, Revenue 2.44b/2.23b)
GMI: 1.00 (GM 96.59% / 96.48%)
AQI: 0.90 (AQ_t 0.36 / AQ_t-1 0.40)
SGI: 1.09 (Revenue 2.44b / 2.23b)
TATA: -0.13 (NI 860.6m - CFO 1.18b) / TA 2.49b)
Beneish M = -2.99 (Cap -4..+1) = A
What is the price of EXEL shares?

As of August 15, 2026, the stock is trading at USD 51.24 with a total of 1,795,328 shares traded. Over the past week, the price has changed by -5.23%, over one month by -8.12%, over three months by +0.27% and over the past year by +33.19%.

Current recommended Stop Loss: 49.10 (which is 4.2% or 1.2 ATR below the current price).

Is EXEL a buy, sell or hold?

Exelixis has received a consensus analysts rating of 3.90. Therefore, it is recommended to buy EXEL.

  • StrongBuy: 9
  • Buy: 1
  • Hold: 9
  • Sell: 1
  • StrongSell: 0

What are the forecasts/targets for the EXEL price?
Analysts Target Price 52.9 3.3%
Exelixis (EXEL) - Fundamental Data Overview as of 15 August 2026
Market Cap USD = 12.5b (12.5b USD * 1.0 USD.USD)
P/E Trailing = 15.9151
P/E Forward = 16.7224
P/S = 5.148
P/B = 7.1213
P/EG = 2.2685
Revenue TTM = 2.44b USD
EBIT TTM = 971.5m USD
EBITDA TTM = 999.8m USD
 Long Term Debt = unknown (none)
 Short Term Debt = unknown (none)
 Debt = 165.9m USD (from shortLongTermDebtTotal, last quarter) (leases 165.9m already included)
Net Debt = -673.5m USD (calculated: Debt 165.9m - CCE 839.4m)
Enterprise Value = 11.9b USD (12.5b + Debt 165.9m - CCE 839.4m)
 Interest Coverage Ratio = unknown (Ebit TTM 971.5m / Interest Expense TTM 0.0)
 EV/FCF = 10.05x (Enterprise Value 11.9b / FCF TTM 1.18b)
FCF Yield = 9.95% (FCF TTM 1.18b / Enterprise Value 11.9b)
FCF Margin = 48.47% (FCF TTM 1.18b / Revenue TTM 2.44b)
Net Margin = 35.33% (Net Income TTM 860.6m / Revenue TTM 2.44b)
 Gross Margin = unknown ((Revenue TTM 2.44b - Cost of Revenue TTM 85.7m) / Revenue TTM)
 Tobins Q-Ratio = 4.76 (Enterprise Value 11.9b / Total Assets 2.49b)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 165.9m)
Taxrate = 16.89% (174.8m / 1.04b)
NOPAT = 807.5m (EBIT 971.5m * (1 - 16.89%))
Current Ratio = 3.46 (Total Current Assets 1.25b / Total Current Liabilities 361.9m)
Debt / Equity = 0.09 (Debt 165.9m / totalStockholderEquity, last quarter 1.84b)
Debt / EBITDA = -0.67 (Net Debt -673.5m / EBITDA 999.8m)
Debt / FCF = -0.57 (Net Debt -673.5m / FCF TTM 1.18b)
Total Stockholder Equity = 2.03b (last 4 quarters mean from totalStockholderEquity)
RoA = 33.28% (Net Income 860.6m / Total Assets 2.49b)
RoE = 42.49% (Net Income TTM 860.6m / Total Stockholder Equity 2.03b)
RoCE = 45.56% (EBIT 971.5m / Capital Employed (Total Assets 2.49b - Current Liab 361.9m))
RoIC = 40.16% (NOPAT 807.5m / Invested Capital 2.01b)
WACC = 9.07% (E(12.5b)/V(12.7b) * Re(9.19%) + D(165.9m)/V(12.7b) * Rd(0.0%) * (1-Tc(0.17)))
Discount Rate = 9.19% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: -92.66 | Cagr: -6.97%
[DCF] Terminal Value 75.67% ; FCFF base≈997.6m ; Y1≈1.14b ; Y5≈1.68b
[DCF] Fair Price = 93.44 (EV 22.5b - Net Debt -673.5m = Equity 23.2b / Shares 247.8m; r=9.07% [WACC]; 5y FCF grow 15.0% → 2.50% )
EPS Correlation: 95.02 | EPS CAGR: 87.14% | SUE: 0.50 | # QB: 0
Revenue Correlation: 96.27 | Revenue CAGR: 12.36% | SUE: -0.03 | # QB: 0
EPS current Quarter (2026-09-30): EPS=0.91 | Chg30d=+2.42% | Revisions=-29% | Analysts=11
EPS current Year (2026-12-31): EPS=3.57 | Chg30d=+1.01% | Revisions=-12% | GrowthEPS=+15.8% | GrowthRev=+10.0%
EPS next Year (2027-12-31): EPS=4.07 | Chg30d=+1.98% | Revisions=+0% | GrowthEPS=+14.1% | GrowthRev=+12.7%
[Analyst] Revisions Ratio: -19% (up=5, down=8)