(EXEL) Exelixis - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US30161Q1040

Stock: Cancer, Medicines, Tablets, Capsules, Inhibitors

Total Rating 54
Risk 87
Buy Signal 0.40

EPS (Earnings per Share)

EPS (Earnings per Share) of EXEL over the last years for every Quarter: "2020-12": 0.09, "2021-03": 0.005, "2021-06": 0.3, "2021-09": 0.12, "2021-12": 0.29, "2022-03": 0.21, "2022-06": 0.22, "2022-09": 0.23, "2022-12": -0.09, "2023-03": 0.12, "2023-06": 0.25, "2023-09": 0.1, "2023-12": 0.27, "2024-03": 0.2, "2024-06": 0.77, "2024-09": 0.4, "2024-12": 0.55, "2025-03": 0.62, "2025-06": 0.65, "2025-09": 0.78, "2025-12": 0,

Revenue

Revenue of EXEL over the last years for every Quarter: 2020-12: 270.052, 2021-03: 270.23, 2021-06: 385.177, 2021-09: 328.423, 2021-12: 451.14, 2022-03: 355.98, 2022-06: 419.427, 2022-09: 411.738, 2022-12: 423.917, 2023-03: 408.788, 2023-06: 469.848, 2023-09: 471.92, 2023-12: 479.652, 2024-03: 425.226, 2024-06: 637.178, 2024-09: 539.542, 2024-12: 566.755, 2025-03: 555.447, 2025-06: 568.261, 2025-09: 597.755, 2025-12: null,
Risk 5d forecast
Volatility 40.4%
Relative Tail Risk -20.9%
Reward TTM
Sharpe Ratio 0.73
Alpha 19.69
Character TTM
Beta 0.611
Beta Downside 0.248
Drawdowns 3y
Max DD 25.34%
CAGR/Max DD 1.43

Description: EXEL Exelixis January 02, 2026

Exelixis, Inc. (NASDAQ:EXEL) is a U.S.–focused oncology biotech that commercializes cabozantinib-based therapies-CABOMETYX for advanced renal cell carcinoma (RCC) post-anti-angiogenic treatment and COMETRIQ for progressive/metastatic medullary thyroid cancer-while maintaining a broader pipeline of kinase inhibitors, an ADC (XB010), and a MEK inhibitor combination (COTELLIC). All marketed products share the same core molecule, cabozantinib, which blocks MET, AXL, RET, and VEGF receptors.

Beyond its approved drugs, Exelixis is advancing several late-stage candidates: zanzalintinib (next-gen TKI targeting VEGF, MET, and TAM kinases), XL309 (USP1 inhibitor for BRCA-mutated tumors), and XL495 (PKMYT1 inhibitor). The firm leverages a network of collaborations with major pharma-Roche, Takeda, Merck, Bristol-Myers Squibb, among others-to share development risk and accelerate market entry. As of FY 2023, CABOMETYX generated roughly 70 % of the company’s $1.5 billion total revenue, and COMETRIQ contributed an additional $150 million, underscoring the cash-flow reliance on a narrow product set.

Sector-level drivers that materially affect Exelixis include the expanding global RCC market (projected CAGR ≈ 6 % through 2028) and the broader biotech trend of increasing R&D intensity, with industry-average R&D spend now exceeding 20 % of sales. Exelixis’ 2024 guidance assumes a 5-6 % growth in CABOMETYX sales, contingent on maintaining market share against emerging TKIs and on the successful regulatory filing of zanzalintinib. For a deeper dive into how these dynamics translate into valuation metrics, a quick look at ValueRay’s analyst toolkit may be worthwhile.

Piotroski VR‑10 (Strict, 0-10) 6.5

Net Income: 677.9m TTM > 0 and > 6% of Revenue
FCF/TA: 0.27 > 0.02 and ΔFCF/TA 12.99 > 1.0
NWC/Revenue: 44.95% < 20% (prev 55.50%; Δ -10.56% < -1%)
CFO/TA 0.28 > 3% & CFO 791.0m > Net Income 677.9m
Net Debt (-199.8m) to EBITDA (862.9m): -0.23 < 3
Current Ratio: 3.75 > 1.5 & < 3
Outstanding Shares: last quarter (278.5m) vs 12m ago -4.44% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 79.12% > 50% (prev 70.32%; Δ 8.81% > 0%)
Interest Coverage Ratio: -20.75 > 6 (EBITDA TTM 862.9m / Interest Expense TTM -40.1m)

Altman Z'' 4.04

A: 0.36 (Total Current Assets 1.40b - Total Current Liabilities 373.8m) / Total Assets 2.82b
B: -0.04 (Retained Earnings -106.1m / Total Assets 2.82b)
C: 0.29 (EBIT TTM 833.1m / Avg Total Assets 2.89b)
D: -0.15 (Book Value of Equity -102.2m / Total Liabilities 662.8m)
Altman-Z'' Score: 4.04 = AA

Beneish M -2.86

DSRI: 1.04 (Receivables 309.7m/269.7m, Revenue 2.29b/2.08b)
GMI: 1.00 (GM 96.63% / 96.25%)
AQI: 1.18 (AQ_t 0.38 / AQ_t-1 0.32)
SGI: 1.10 (Revenue 2.29b / 2.08b)
TATA: -0.04 (NI 677.9m - CFO 791.0m) / TA 2.82b)
Beneish M-Score: -2.86 (Cap -4..+1) = A

What is the price of EXEL shares?

As of February 07, 2026, the stock is trading at USD 43.90 with a total of 3,364,665 shares traded.
Over the past week, the price has changed by +6.14%, over one month by +0.50%, over three months by +7.60% and over the past year by +30.38%.

Is EXEL a buy, sell or hold?

Exelixis has received a consensus analysts rating of 3.90. Therefore, it is recommended to buy EXEL.
  • StrongBuy: 7
  • Buy: 4
  • Hold: 9
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the EXEL price?

Issuer Target Up/Down from current
Wallstreet Target Price 45.8 4.4%
Analysts Target Price 45.8 4.4%
ValueRay Target Price 54.3 23.6%

EXEL Fundamental Data Overview February 05, 2026

P/E Trailing = 17.895
P/E Forward = 13.3511
P/S = 5.0106
P/B = 5.1328
P/EG = 2.2685
Revenue TTM = 2.29b USD
EBIT TTM = 833.1m USD
EBITDA TTM = 862.9m USD
Long Term Debt = 176.5m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 25.0m USD (from shortTermDebt, last fiscal year)
Debt = 176.5m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -199.8m USD (from netDebt column, last quarter)
Enterprise Value = 10.65b USD (11.47b + Debt 176.5m - CCE 988.5m)
Interest Coverage Ratio = -20.75 (Ebit TTM 833.1m / Interest Expense TTM -40.1m)
EV/FCF = 14.15x (Enterprise Value 10.65b / FCF TTM 753.1m)
FCF Yield = 7.07% (FCF TTM 753.1m / Enterprise Value 10.65b)
FCF Margin = 32.91% (FCF TTM 753.1m / Revenue TTM 2.29b)
Net Margin = 29.63% (Net Income TTM 677.9m / Revenue TTM 2.29b)
Gross Margin = unknown ((Revenue TTM 2.29b - Cost of Revenue TTM 77.2m) / Revenue TTM)
Tobins Q-Ratio = 3.77 (Enterprise Value 10.65b / Total Assets 2.82b)
Interest Expense / Debt = 14.91% (Interest Expense 26.3m / Debt 176.5m)
Taxrate = 23.31% (58.8m / 252.4m)
NOPAT = 638.9m (EBIT 833.1m * (1 - 23.31%))
Current Ratio = 3.75 (Total Current Assets 1.40b / Total Current Liabilities 373.8m)
Debt / Equity = 0.08 (Debt 176.5m / totalStockholderEquity, last quarter 2.16b)
Debt / EBITDA = -0.23 (Net Debt -199.8m / EBITDA 862.9m)
Debt / FCF = -0.27 (Net Debt -199.8m / FCF TTM 753.1m)
Total Stockholder Equity = 2.14b (last 4 quarters mean from totalStockholderEquity)
RoA = 23.44% (Net Income 677.9m / Total Assets 2.82b)
RoE = 31.64% (Net Income TTM 677.9m / Total Stockholder Equity 2.14b)
RoCE = 35.93% (EBIT 833.1m / Capital Employed (Equity 2.14b + L.T.Debt 176.5m))
RoIC = 29.82% (NOPAT 638.9m / Invested Capital 2.14b)
WACC = 8.22% (E(11.47b)/V(11.64b) * Re(8.17%) + D(176.5m)/V(11.64b) * Rd(14.91%) * (1-Tc(0.23)))
Discount Rate = 8.17% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: -100.0 | Cagr: -5.67%
[DCF Debug] Terminal Value 79.26% ; FCFF base≈613.8m ; Y1≈705.8m ; Y5≈988.2m
Fair Price DCF = 61.35 (EV 16.25b - Net Debt -199.8m = Equity 16.45b / Shares 268.1m; r=8.22% [WACC]; 5y FCF grow 17.57% → 2.90% )
EPS Correlation: 53.50 | EPS CAGR: -24.31% | SUE: -4.0 | # QB: 0
Revenue Correlation: 84.14 | Revenue CAGR: 7.79% | SUE: 0.04 | # QB: 0
EPS next Quarter (2026-03-31): EPS=0.76 | Chg30d=+0.062 | Revisions Net=+0 | Analysts=4
EPS next Year (2026-12-31): EPS=3.43 | Chg30d=+0.147 | Revisions Net=+2 | Growth EPS=+15.8% | Growth Revenue=+11.9%

Additional Sources for EXEL Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle