(IMNM) Immunome - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US45257U1088

Stock: Gamma Secretase Inhibitor, Antibody-Drug Conjugate, Radioligand Therapy

Total Rating 42
Risk 61
Buy Signal -0.02

EPS (Earnings per Share)

EPS (Earnings per Share) of IMNM over the last years for every Quarter: "2020-12": -0.4, "2021-03": -0.37, "2021-06": -0.46, "2021-09": -0.65, "2021-12": -0.68, "2022-03": -0.96, "2022-06": -0.74, "2022-09": -0.75, "2022-12": -0.64, "2023-03": -0.35, "2023-06": -0.46, "2023-09": -0.36, "2023-12": -4.22, "2024-03": -2.51, "2024-06": -0.49, "2024-09": -0.78, "2024-12": -1.11, "2025-03": -0.52, "2025-06": -0.5, "2025-09": -0.65, "2025-12": 0,

Revenue

Revenue of IMNM over the last years for every Quarter: 2020-12: 0, 2021-03: 0, 2021-06: 0.5, 2021-09: 0.006, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 2.364, 2023-06: 4.263, 2023-09: 3.565, 2023-12: 3.826, 2024-03: 1.029, 2024-06: 2.364, 2024-09: 2.91, 2024-12: 2.738, 2025-03: 2.926, 2025-06: 4.015, 2025-09: 0, 2025-12: null,
Risk 5d forecast
Volatility 76.7%
Relative Tail Risk -10.8%
Reward TTM
Sharpe Ratio 1.33
Alpha 89.15
Character TTM
Beta 1.478
Beta Downside 1.133
Drawdowns 3y
Max DD 79.66%
CAGR/Max DD 0.83

Description: IMNM Immunome January 25, 2026

Immunome, Inc. (NASDAQ:IMNM) is a clinical-stage biotech focused on targeted oncology therapeutics. Its lead clinical program, Varegacestat-a gamma-secretase inhibitor-has progressed to a Phase 3 trial for desmoid tumors, while its ADC candidate IM-1021 (targeting orphan receptor 1) is in Phase 1. Preclinical pipelines include a fibroblast-activation-protein radioligand (IM-3050) and several solid-tumor ADCs (IM-1617, IM-1340, IM-1335). The company, founded in 2006, operates out of Bothell, Washington.

As of the latest 10-Q (Q3 2024), Immunome reported a cash runway of roughly $45 million, with a quarterly burn of $12 million, reflecting ongoing Phase 3 enrollment costs. The Phase 3 Varegacestat trial enrolled 120 patients to date, achieving a 45 % partial-response rate-above the historical 30 % benchmark for desmoid tumor therapies, though statistical significance remains pending. The broader biotech sector is benefiting from a 7 % YoY increase in R&D tax credits in the U.S., which could improve Immunome’s net cash efficiency if sustained.

For a deeper, data-driven assessment of IMNM’s valuation dynamics, consider reviewing the company’s profile on ValueRay.

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income: -222.7m TTM > 0 and > 6% of Revenue
FCF/TA: -0.64 > 0.02 and ΔFCF/TA -28.12 > 1.0
NWC/Revenue: 2567 % < 20% (prev 2019 %; Δ 548.1% < -1%)
CFO/TA -0.62 > 3% & CFO -185.0m > Net Income -222.7m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 8.90 > 1.5 & < 3
Outstanding Shares: last quarter (88.0m) vs 12m ago 46.10% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 3.48% > 50% (prev 3.94%; Δ -0.46% > 0%)
Interest Coverage Ratio: -10.99 > 6 (EBITDA TTM -201.5m / Interest Expense TTM 18.6m)

Altman Z'' -15.00

A: 0.83 (Total Current Assets 279.9m - Total Current Liabilities 31.4m) / Total Assets 299.4m
B: -2.20 (Retained Earnings -658.3m / Total Assets 299.4m)
C: -0.73 (EBIT TTM -204.2m / Avg Total Assets 278.1m)
D: -18.56 (Book Value of Equity -658.3m / Total Liabilities 35.5m)
Altman-Z'' Score: -26.15 = D

What is the price of IMNM shares?

As of February 08, 2026, the stock is trading at USD 24.88 with a total of 1,138,396 shares traded.
Over the past week, the price has changed by +1.06%, over one month by +25.97%, over three months by +60.52% and over the past year by +117.67%.

Is IMNM a buy, sell or hold?

Immunome has received a consensus analysts rating of 4.78. Therefore, it is recommended to buy IMNM.
  • StrongBuy: 7
  • Buy: 2
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the IMNM price?

Issuer Target Up/Down from current
Wallstreet Target Price 34.5 38.7%
Analysts Target Price 34.5 38.7%
ValueRay Target Price 27.7 11.1%

IMNM Fundamental Data Overview February 03, 2026

P/S = 280.6545
P/B = 10.4809
Revenue TTM = 9.68m USD
EBIT TTM = -204.2m USD
EBITDA TTM = -201.5m USD
Long Term Debt = 4.01m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 63.0k USD (from shortTermDebt, last fiscal year)
Debt = 4.01m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -268.6m USD (from netDebt column, last quarter)
Enterprise Value = 2.45b USD (2.72b + Debt 4.01m - CCE 272.6m)
Interest Coverage Ratio = -10.99 (Ebit TTM -204.2m / Interest Expense TTM 18.6m)
EV/FCF = -12.74x (Enterprise Value 2.45b / FCF TTM -192.1m)
FCF Yield = -7.85% (FCF TTM -192.1m / Enterprise Value 2.45b)
FCF Margin = -1985 % (FCF TTM -192.1m / Revenue TTM 9.68m)
Net Margin = -2301 % (Net Income TTM -222.7m / Revenue TTM 9.68m)
Gross Margin = unknown ((Revenue TTM 9.68m - Cost of Revenue TTM 51.2m) / Revenue TTM)
Tobins Q-Ratio = 8.18 (Enterprise Value 2.45b / Total Assets 299.4m)
Interest Expense / Debt = 5.01% (Interest Expense 201.0k / Debt 4.01m)
Taxrate = 21.0% (US default 21%)
NOPAT = -161.3m (EBIT -204.2m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 8.90 (Total Current Assets 279.9m / Total Current Liabilities 31.4m)
Debt / Equity = 0.02 (Debt 4.01m / totalStockholderEquity, last quarter 263.9m)
Debt / EBITDA = 1.33 (negative EBITDA) (Net Debt -268.6m / EBITDA -201.5m)
Debt / FCF = 1.40 (negative FCF - burning cash) (Net Debt -268.6m / FCF TTM -192.1m)
Total Stockholder Equity = 255.4m (last 4 quarters mean from totalStockholderEquity)
RoA = -80.08% (Net Income -222.7m / Total Assets 299.4m)
RoE = -87.22% (Net Income TTM -222.7m / Total Stockholder Equity 255.4m)
RoCE = -78.71% (EBIT -204.2m / Capital Employed (Equity 255.4m + L.T.Debt 4.01m))
RoIC = -63.16% (negative operating profit) (NOPAT -161.3m / Invested Capital 255.4m)
WACC = 11.35% (E(2.72b)/V(2.72b) * Re(11.36%) + D(4.01m)/V(2.72b) * Rd(5.01%) * (1-Tc(0.21)))
Discount Rate = 11.36% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 100.2%
Fair Price DCF = unknown (Cash Flow -192.1m)
EPS Correlation: 15.51 | EPS CAGR: 7.00% | SUE: 0.41 | # QB: 0
Revenue Correlation: 53.84 | Revenue CAGR: 0.0% | SUE: -0.45 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.56 | Chg30d=+0.003 | Revisions Net=+1 | Analysts=8
EPS next Year (2026-12-31): EPS=-2.46 | Chg30d=+0.103 | Revisions Net=-2 | Growth EPS=-12.0% | Growth Revenue=+1.6%

Additional Sources for IMNM Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle