(LYEL) Lyell Immunopharma - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US55083R1041

LYEL: Cancer, Cell, Therapy, Treatment, Tumors, Immunotherapy

Lyell Immunopharma, Inc. (NASDAQ: LYEL) is a clinical-stage biotechnology company specializing in the development of innovative T cell therapies for solid tumor treatments. The company leverages proprietary ex vivo genetic and epigenetic reprogramming technologies to enhance T cell functionality and persistence. Its platform includes c Jun overexpression to mitigate T cell exhaustion and NR4A3 gene knockout to improve T cell resilience. Additionally, Lyell employs Epi R and Stim R technologies to generate T cells with enhanced stemness and synthetic cell mimetics for sustained anti-tumor activity.

The companys pipeline includes LYL797, a ROR1-targeting CAR T cell product candidate currently in Phase 1 clinical trials for solid tumors. LYL845, an epigenetically reprogrammed tumor-infiltrating lymphocyte (TIL) product, is also in Phase 1 trials for multiple solid tumor indications. Preclinical development includes LYL119, a next-generation ROR1 CAR T-cell product designed for enhanced cytotoxicity, and a second-generation TIL product aimed at improving efficacy in solid tumor treatments.

Lyell Immunopharma, founded in 2018 and headquartered in South San Francisco, California, focuses on addressing the limitations of current cell therapies through its cutting-edge reprogramming approaches. For more information, visit their website at https://lyell.com.

3-Month Forecast: Based on the provided data, Lyell Immunopharmas stock (NASDAQ: LYEL) is expected to experience volatility due to its micro-cap nature and clinical-stage risks. Technically, the stock is trading below its 200-day SMA of $1.29, indicating potential long-term bearish pressure. However, the recent price of $0.66 is slightly above its 20-day and 50-day SMAs, suggesting short-term stability. The ATR of $0.05 reflects low volatility, which may persist in the near term. Fundamentally, the companys high P/S ratio of 3296.33 highlights market expectations for growth, though the negative RoE of -38.44% and low P/B ratio of 0.39 signal financial challenges. Overall, the stock may see a modest recovery in the short term but faces longer-term headwinds due to its developmental stage and financial metrics.

Additional Sources for LYEL Stock

LYEL Stock Overview

Market Cap in USD 208m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2021-06-17

LYEL Stock Ratings

Growth 5y -84.6%
Fundamental -
Dividend 0.0%
Rel. Strength Industry -71.3
Analysts 2.75/5
Fair Price Momentum 0.28 USD
Fair Price DCF -

LYEL Dividends

No Dividends Paid

LYEL Growth Ratios

Growth Correlation 3m 8.8%
Growth Correlation 12m -93.4%
Growth Correlation 5y -93.8%
CAGR 5y -59.25%
CAGR/Max DD 5y -0.61
Sharpe Ratio 12m -1.27
Alpha -86.19
Beta 1.30
Volatility 81.57%
Current Volume 1017.3k
Average Volume 20d 860.5k
What is the price of LYEL stocks?
As of March 15, 2025, the stock is trading at USD 0.59 with a total of 1,017,265 shares traded.
Over the past week, the price has changed by -21.23%, over one month by -4.05%, over three months by -12.68% and over the past year by -73.51%.
Is Lyell Immunopharma a good stock to buy?
No, based on ValueRay Analyses, Lyell Immunopharma (NASDAQ:LYEL) is currently (March 2025) a stock to sell. It has a ValueRay Growth Rating of -84.64 and therefor a clear technical negative rating according to historical growth.
Based on ValueRays Analyses, Dividends and Discounted-Cash-Flow, the Fair Value of LYEL as of March 2025 is 0.28. This means that LYEL is currently overvalued and has a potential downside of -52.54%.
Is LYEL a buy, sell or hold?
Lyell Immunopharma has received a consensus analysts rating of 2.75. Therefor, it is recommend to hold LYEL.
  • Strong Buy: 0
  • Buy: 0
  • Hold: 3
  • Sell: 1
  • Strong Sell: 0
What are the forecast for LYEL stock price target?
According to ValueRays Forecast Model, LYEL Lyell Immunopharma will be worth about 0.3 in March 2026. The stock is currently trading at 0.59. This means that the stock has a potential downside of -47.46%.
Issuer Forecast Upside
Wallstreet Target Price 0.8 35.6%
Analysts Target Price 0.8 35.6%
ValueRay Target Price 0.3 -47.5%