(NTLA) Intellia Therapeutics - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US45826J1051

Stock: Gene Editing, In Vivo, CAR-T, NK Cell, Autoimmune

Total Rating 31
Risk 36
Buy Signal -0.40

EPS (Earnings per Share)

EPS (Earnings per Share) of NTLA over the last years for every Quarter: "2020-12": -0.69, "2021-03": -0.69, "2021-06": -1.01, "2021-09": -0.97, "2021-12": -1.09, "2022-03": -1.96, "2022-06": -1.33, "2022-09": -1.49, "2022-12": -1.4, "2023-03": -1.17, "2023-06": -1.4, "2023-09": -1.38, "2023-12": -1.46, "2024-03": -1.12, "2024-06": -1.52, "2024-09": -1.34, "2024-12": -1.27, "2025-03": -1.1, "2025-06": -0.98, "2025-09": -0.92, "2025-12": 0,

Revenue

Revenue of NTLA over the last years for every Quarter: 2020-12: 6.595, 2021-03: 6.445, 2021-06: 6.55, 2021-09: 7.204, 2021-12: 12.854, 2022-03: 11.252, 2022-06: 14.03, 2022-09: 13.266, 2022-12: 13.573, 2023-03: 12.606, 2023-06: 13.594, 2023-09: 11.992, 2023-12: -1.917, 2024-03: 28.935, 2024-06: 6.957, 2024-09: 9.111, 2024-12: 12.874, 2025-03: 16.627, 2025-06: 14.245, 2025-09: 13.782, 2025-12: null,
Risk 5d forecast
Volatility 97.8%
Relative Tail Risk -7.18%
Reward TTM
Sharpe Ratio 0.69
Alpha -4.56
Character TTM
Beta 1.499
Beta Downside 1.108
Drawdowns 3y
Max DD 86.36%
CAGR/Max DD -0.38

Description: NTLA Intellia Therapeutics January 20, 2026

Intellia Therapeutics (NASDAQ:NTLA) is a Cambridge-based, clinical-stage biotech that develops curative in-vivo genome-editing therapies using its CRISPR-Cas9 platform. Its lead candidates are NTLA-2001 (Phase 1 for transthyretin amyloidosis) and NTLA-2002 (Phase 1/2 for hereditary angioedema). The firm also pursues engineered cell-therapy programs, partnering with AvenCell (allogeneic universal CAR-T), Kyverna (CD19 CAR-T for B-cell autoimmune disease), ONK Therapeutics (engineered NK cells) and ReCode Therapeutics (genomic medicines for cystic fibrosis).

Key recent metrics: as of Q2 2024 Intellia reported $210 million of cash and marketable securities, a cash-burn rate of roughly $120 million per year, and a market capitalization near $7 billion. The broader CRISPR-based therapeutics market is projected to grow at a 15-18% CAGR through 2030, driven by expanding FDA acceptance of gene-editing modalities and increasing payer willingness to fund curative treatments.

For a deeper look at NTLA’s valuation and risk profile, you may find ValueRay’s analyst notes worth reviewing.

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income: -445.8m TTM > 0 and > 6% of Revenue
FCF/TA: -0.45 > 0.02 and ΔFCF/TA -13.65 > 1.0
NWC/Revenue: 848.7% < 20% (prev 1405 %; Δ -556.0% < -1%)
CFO/TA -0.44 > 3% & CFO -410.6m > Net Income -445.8m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 6.21 > 1.5 & < 3
Outstanding Shares: last quarter (110.2m) vs 12m ago 9.09% < -2%
Gross Margin: -41.70% > 18% (prev 0.76%; Δ -4246 % > 0.5%)
Asset Turnover: 5.48% > 50% (prev 3.67%; Δ 1.81% > 0%)
Interest Coverage Ratio: -20.58 > 6 (EBITDA TTM -456.1m / Interest Expense TTM -22.8m)

Altman Z'' -15.00

A: 0.53 (Total Current Assets 581.9m - Total Current Liabilities 93.7m) / Total Assets 925.3m
B: -2.70 (Retained Earnings -2.49b / Total Assets 925.3m)
C: -0.45 (EBIT TTM -468.6m / Avg Total Assets 1.05b)
D: -14.10 (Book Value of Equity -2.49b / Total Liabilities 176.9m)
Altman-Z'' Score: -23.13 = D

Beneish M -3.01

DSRI: 0.93 (Receivables 11.1m/8.85m, Revenue 57.5m/43.1m)
GMI: 1.00 (fallback, negative margins)
AQI: 0.78 (AQ_t 0.22 / AQ_t-1 0.28)
SGI: 1.34 (Revenue 57.5m / 43.1m)
TATA: -0.04 (NI -445.8m - CFO -410.6m) / TA 925.3m)
Beneish M-Score: -3.01 (Cap -4..+1) = AA

What is the price of NTLA shares?

As of February 07, 2026, the stock is trading at USD 12.28 with a total of 4,610,471 shares traded.
Over the past week, the price has changed by -6.62%, over one month by +26.21%, over three months by -0.32% and over the past year by +21.22%.

Is NTLA a buy, sell or hold?

Intellia Therapeutics has received a consensus analysts rating of 4.34. Therefore, it is recommended to buy NTLA.
  • StrongBuy: 18
  • Buy: 4
  • Hold: 6
  • Sell: 1
  • StrongSell: 0

What are the forecasts/targets for the NTLA price?

Issuer Target Up/Down from current
Wallstreet Target Price 23.9 94.3%
Analysts Target Price 23.9 94.3%
ValueRay Target Price 9.5 -23%

NTLA Fundamental Data Overview February 04, 2026

P/S = 26.2957
P/B = 2.1512
P/EG = -0.0969
Revenue TTM = 57.5m USD
EBIT TTM = -468.6m USD
EBITDA TTM = -456.1m USD
Long Term Debt = 98.0m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 27.4m USD (from shortTermDebt, last quarter)
Debt = 98.0m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -95.4m USD (from netDebt column, last quarter)
Enterprise Value = 1.10b USD (1.51b + Debt 98.0m - CCE 511.0m)
Interest Coverage Ratio = -20.58 (Ebit TTM -468.6m / Interest Expense TTM -22.8m)
EV/FCF = -2.67x (Enterprise Value 1.10b / FCF TTM -412.6m)
FCF Yield = -37.52% (FCF TTM -412.6m / Enterprise Value 1.10b)
FCF Margin = -717.3% (FCF TTM -412.6m / Revenue TTM 57.5m)
Net Margin = -774.9% (Net Income TTM -445.8m / Revenue TTM 57.5m)
Gross Margin = -41.70% ((Revenue TTM 57.5m - Cost of Revenue TTM 81.5m) / Revenue TTM)
Gross Margin QoQ = none% (prev 100.0%)
Tobins Q-Ratio = 1.19 (Enterprise Value 1.10b / Total Assets 925.3m)
Interest Expense / Debt = 9.02% (Interest Expense 8.83m / Debt 98.0m)
Taxrate = 21.0% (US default 21%)
NOPAT = -370.2m (EBIT -468.6m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 6.21 (Total Current Assets 581.9m / Total Current Liabilities 93.7m)
Debt / Equity = 0.13 (Debt 98.0m / totalStockholderEquity, last quarter 748.4m)
Debt / EBITDA = 0.21 (negative EBITDA) (Net Debt -95.4m / EBITDA -456.1m)
Debt / FCF = 0.23 (negative FCF - burning cash) (Net Debt -95.4m / FCF TTM -412.6m)
Total Stockholder Equity = 778.9m (last 4 quarters mean from totalStockholderEquity)
RoA = -42.49% (Net Income -445.8m / Total Assets 925.3m)
RoE = -57.24% (Net Income TTM -445.8m / Total Stockholder Equity 778.9m)
RoCE = -53.44% (EBIT -468.6m / Capital Employed (Equity 778.9m + L.T.Debt 98.0m))
RoIC = -47.53% (negative operating profit) (NOPAT -370.2m / Invested Capital 778.9m)
WACC = 11.18% (E(1.51b)/V(1.61b) * Re(11.44%) + D(98.0m)/V(1.61b) * Rd(9.02%) * (1-Tc(0.21)))
Discount Rate = 11.44% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 10.37%
Fair Price DCF = unknown (Cash Flow -412.6m)
EPS Correlation: 68.08 | EPS CAGR: 108.3% | SUE: 4.0 | # QB: 1
Revenue Correlation: -1.37 | Revenue CAGR: 1.88% | SUE: -0.03 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.99 | Chg30d=+0.000 | Revisions Net=+1 | Analysts=8
EPS next Year (2026-12-31): EPS=-3.60 | Chg30d=-0.017 | Revisions Net=+1 | Growth EPS=+9.9% | Growth Revenue=-10.0%

Additional Sources for NTLA Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle