(RGLS) Regulus Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US75915K3095

RGLS: MicroRNA, Oligonucleotides, Kidney, Disease, Treatment

Regulus Therapeutics Inc. (NASDAQ:RGLS) is a clinical-stage biopharmaceutical company pioneering the discovery and development of microRNA-targeted therapies. The companys lead candidate, RGLS8429, is an anti-miR oligonucleotide designed to inhibit miR-17 and is currently in a Phase 1b clinical trial for autosomal dominant polycystic kidney disease (ADPKD). Regulus employs a proprietary technology platform to develop organ-selective delivery strategies, enhancing the efficacy and safety of its candidates. The company, established in 2007 and headquartered in San Diego, California, is advancing a preclinical pipeline targeting various diseases through microRNA modulation.

Regulus Therapeutics Inc. focuses on leveraging microRNA biology to address unmet medical needs. By targeting specific microRNAs, the company aims to develop therapies that modulate gene expression implicated in disease pathways. RGLS8429, for instance, targets miR-17, which plays a role in fibrosis and cyst formation in ADPKD. The companys approach emphasizes precision in drug delivery to improve therapeutic outcomes. With a strong foundation in RNA biology, Regulus is positioned to explore new frontiers in disease treatment.

Over the next three months, Regulus Therapeutics Inc. (RGLS) is expected to exhibit a neutral trend based on technical indicators. The stock is currently trading below its 20-day and 50-day simple moving averages (SMA) of $1.27 and $1.32, respectively, but above its 200-day SMA of $1.62. This configuration suggests a potential consolidation phase. The average true range (ATR) of $0.12 indicates low volatility, which may persist unless significant news or data emerges. The relative strength index (RSI) is near 40, suggesting the stock is not overbought or oversold. Fundamental analysis highlights a market capitalization of $88.43 million, with a price-to-book (P/B) ratio of 1.02, indicating the stock is trading near its book value. The companys negative return on equity (RoE) of -47.96% reflects its developmental stage. Overall, the stock is likely to remain range-bound with potential upside if it breaks above the 50-day SMA, driven by clinical trial progress or partnership announcements.

Additional Sources for RGLS Stock

RGLS Stock Overview

Market Cap in USD 154m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2012-10-04

RGLS Stock Ratings

Growth Rating -53.5
Fundamental -42.2
Dividend Rating 0.0
Rel. Strength 24.4
Analysts 4.5/5
Fair Price Momentum 2.63 USD
Fair Price DCF -

RGLS Dividends

No Dividends Paid

RGLS Growth Ratios

Growth Correlation 3m 92.7%
Growth Correlation 12m -60.5%
Growth Correlation 5y -76.8%
CAGR 5y -10.08%
CAGR/Max DD 5y -0.11
Sharpe Ratio 12m -0.05
Alpha 13.45
Beta 0.600
Volatility 113.80%
Current Volume 898.6k
Average Volume 20d 866.3k
What is the price of RGLS stocks?
As of April 26, 2025, the stock is trading at USD 2.76 with a total of 898,578 shares traded.
Over the past week, the price has changed by +37.31%, over one month by +112.31%, over three months by +131.93% and over the past year by +21.59%.
Is Regulus Therapeutics a good stock to buy?
Probably not. Based on ValueRay Fundamental Analyses, Regulus Therapeutics (NASDAQ:RGLS) is currently (April 2025) not a good stock to buy. It has a ValueRay Fundamental Rating of -42.20 and therefor a somewhat negative outlook according to the companies health.
Based on ValueRays Analyses, Dividends and Discounted-Cash-Flow, the Fair Value of RGLS as of April 2025 is 2.63. This means that RGLS is currently overvalued and has a potential downside of -4.71%.
Is RGLS a buy, sell or hold?
Regulus Therapeutics has received a consensus analysts rating of 4.50. Therefor, it is recommend to buy RGLS.
  • Strong Buy: 4
  • Buy: 1
  • Hold: 1
  • Sell: 0
  • Strong Sell: 0
What are the forecast for RGLS stock price target?
According to ValueRays Forecast Model, RGLS Regulus Therapeutics will be worth about 2.9 in April 2026. The stock is currently trading at 2.76. This means that the stock has a potential upside of +5.43%.
Issuer Forecast Upside
Wallstreet Target Price 10.8 292.4%
Analysts Target Price 10.3 274.3%
ValueRay Target Price 2.9 5.4%