(XERS) Xeris Pharmaceuticals - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US98422E1038

Stock: Glucagon, Periodic Paralysis, Cushings Syndrome, Hypothyroidism

Total Rating 51
Risk 36
Buy Signal -1.10

EPS (Earnings per Share)

EPS (Earnings per Share) of XERS over the last years for every Quarter: "2020-12": -0.41, "2021-03": -0.3, "2021-06": -0.41, "2021-09": -0.39, "2021-12": -0.42, "2022-03": -0.25, "2022-06": -0.19, "2022-09": -0.16, "2022-12": -0.1, "2023-03": -0.12, "2023-06": -0.14, "2023-09": -0.09, "2023-12": -0.1, "2024-03": -0.14, "2024-06": -0.1, "2024-09": -0.11, "2024-12": -0.03, "2025-03": -0.06, "2025-06": -0.01, "2025-09": 0.0035, "2025-12": 0,

Revenue

Revenue of XERS over the last years for every Quarter: 2020-12: 7.172, 2021-03: 8.195, 2021-06: 8.906, 2021-09: 11.035, 2021-12: 21.669, 2022-03: 22.073, 2022-06: 25.306, 2022-09: 29.725, 2022-12: 33.144, 2023-03: 33.196, 2023-06: 38.008, 2023-09: 48.32, 2023-12: 44.39, 2024-03: 40.638, 2024-06: 48.065, 2024-09: 54.268, 2024-12: 60.099, 2025-03: 60.119, 2025-06: 71.539, 2025-09: 74.38, 2025-12: null,
Risk 5d forecast
Volatility 63.9%
Relative Tail Risk -22.0%
Reward TTM
Sharpe Ratio 1.30
Alpha 76.45
Character TTM
Beta 0.906
Beta Downside 1.399
Drawdowns 3y
Max DD 50.67%
CAGR/Max DD 1.66

Description: XERS Xeris Pharmaceuticals January 20, 2026

Xeris Biopharma Holdings, Inc. (NASDAQ:XERS) is a commercial-stage biopharma focused on chronic endocrine and neurological disorders. Its marketed portfolio includes Gvoke® (stable, ready-to-use glucagon for severe hypoglycemia), Keveyis™ (treatment for primary periodic paralysis variants), and Recorlev™ (cortisol synthesis inhibitor for Cushing’s syndrome). The company’s pipeline features XP-8121, a once-weekly subcutaneous levothyroxine currently in Phase 3 for hypothyroidism.

As of the latest 10-K, Xeris reported approximately $71 million of total revenue in FY 2023, driven primarily by Gvoke sales, and held $158 million in cash and marketable securities, giving it ~12 months of runway at its current burn rate. The glucagon rescue market is projected to grow ~6 % CAGR through 2028, while the Cushing’s-syndrome niche (~$1 billion) remains under-served, positioning Recorlev for potential market share gains pending FDA approval. Xeris’s upcoming regulatory milestones include a PDUFA date for Keveyis in Q3 2024 and a Phase 3 readout for XP-8121 expected late 2024.

For a deeper, data-driven view of XERS’s valuation dynamics, you might find the analyst tools on ValueRay worth a quick look.

Piotroski VR‑10 (Strict, 0-10) 5.0

Net Income: -15.6m TTM > 0 and > 6% of Revenue
FCF/TA: 0.05 > 0.02 and ΔFCF/TA 15.77 > 1.0
NWC/Revenue: 40.51% < 20% (prev 38.31%; Δ 2.20% < -1%)
CFO/TA 0.03 > 3% & CFO 10.6m > Net Income -15.6m
Net Debt (-53.4m) to EBITDA (26.6m): -2.01 < 3
Current Ratio: 1.93 > 1.5 & < 3
Outstanding Shares: last quarter (177.6m) vs 12m ago 19.21% < -2%
Gross Margin: 83.54% > 18% (prev 0.78%; Δ 8275 % > 0.5%)
Asset Turnover: 77.00% > 50% (prev 58.35%; Δ 18.65% > 0%)
Interest Coverage Ratio: 0.47 > 6 (EBITDA TTM 26.6m / Interest Expense TTM 29.6m)

Altman Z'' -5.76

A: 0.29 (Total Current Assets 224.0m - Total Current Liabilities 116.2m) / Total Assets 370.2m
B: -1.84 (Retained Earnings -682.4m / Total Assets 370.2m)
C: 0.04 (EBIT TTM 14.0m / Avg Total Assets 345.6m)
D: -1.84 (Book Value of Equity -682.4m / Total Liabilities 371.1m)
Altman-Z'' Score: -5.76 = D

Beneish M -3.04

DSRI: 0.92 (Receivables 53.8m/41.1m, Revenue 266.1m/187.4m)
GMI: 0.94 (GM 83.54% / 78.47%)
AQI: 0.79 (AQ_t 0.32 / AQ_t-1 0.40)
SGI: 1.42 (Revenue 266.1m / 187.4m)
TATA: -0.07 (NI -15.6m - CFO 10.6m) / TA 370.2m)
Beneish M-Score: -3.04 (Cap -4..+1) = AA

What is the price of XERS shares?

As of February 09, 2026, the stock is trading at USD 7.01 with a total of 948,348 shares traded.
Over the past week, the price has changed by -4.76%, over one month by -13.78%, over three months by -9.20% and over the past year by +96.36%.

Is XERS a buy, sell or hold?

Xeris Pharmaceuticals has received a consensus analysts rating of 4.50. Therefore, it is recommended to buy XERS.
  • StrongBuy: 4
  • Buy: 1
  • Hold: 1
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the XERS price?

Issuer Target Up/Down from current
Wallstreet Target Price 11.1 58.9%
Analysts Target Price 11.1 58.9%
ValueRay Target Price 10 43.1%

XERS Fundamental Data Overview February 05, 2026

P/E Forward = 66.6667
P/S = 4.5762
P/B = 3.3354
Revenue TTM = 266.1m USD
EBIT TTM = 14.0m USD
EBITDA TTM = 26.6m USD
Long Term Debt = 219.5m USD (from longTermDebt, last quarter)
Short Term Debt = 6.19m USD (from shortTermDebt, last quarter)
Debt = 38.2m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -53.4m USD (from netDebt column, last quarter)
Enterprise Value = 1.16b USD (1.22b + Debt 38.2m - CCE 91.6m)
Interest Coverage Ratio = 0.47 (Ebit TTM 14.0m / Interest Expense TTM 29.6m)
EV/FCF = 58.74x (Enterprise Value 1.16b / FCF TTM 19.8m)
FCF Yield = 1.70% (FCF TTM 19.8m / Enterprise Value 1.16b)
FCF Margin = 7.45% (FCF TTM 19.8m / Revenue TTM 266.1m)
Net Margin = -5.88% (Net Income TTM -15.6m / Revenue TTM 266.1m)
Gross Margin = 83.54% ((Revenue TTM 266.1m - Cost of Revenue TTM 43.8m) / Revenue TTM)
Gross Margin QoQ = 85.22% (prev 79.58%)
Tobins Q-Ratio = 3.15 (Enterprise Value 1.16b / Total Assets 370.2m)
Interest Expense / Debt = 19.03% (Interest Expense 7.27m / Debt 38.2m)
Taxrate = 0.0% (0.0 / 621.0k)
NOPAT = 14.0m (EBIT 14.0m * (1 - 0.00%))
Current Ratio = 1.93 (Total Current Assets 224.0m / Total Current Liabilities 116.2m)
Debt / Equity = -44.35 (negative equity) (Debt 38.2m / totalStockholderEquity, last quarter -861.0k)
Debt / EBITDA = -2.01 (Net Debt -53.4m / EBITDA 26.6m)
Debt / FCF = -2.69 (Net Debt -53.4m / FCF TTM 19.8m)
Total Stockholder Equity = -21.2m (last 4 quarters mean from totalStockholderEquity)
RoA = -4.52% (Net Income -15.6m / Total Assets 370.2m)
RoE = 73.68% (negative equity) (Net Income TTM -15.6m / Total Stockholder Equity -21.2m)
RoCE = 7.06% (EBIT 14.0m / Capital Employed (Equity -21.2m + L.T.Debt 219.5m))
RoIC = 6.87% (NOPAT 14.0m / Invested Capital 203.8m)
WACC = 9.55% (E(1.22b)/V(1.26b) * Re(9.25%) + D(38.2m)/V(1.26b) * Rd(19.03%) * (1-Tc(0.0)))
Discount Rate = 9.25% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 13.40%
[DCF Debug] Terminal Value 63.56% ; FCFF base≈19.8m ; Y1≈13.0m ; Y5≈5.94m
Fair Price DCF = 0.87 (EV 91.7m - Net Debt -53.4m = Equity 145.1m / Shares 165.9m; r=9.55% [WACC]; 5y FCF grow -40.0% → 2.90% )
EPS Correlation: 90.04 | EPS CAGR: 138.4% | SUE: -1.70 | # QB: 0
Revenue Correlation: 97.69 | Revenue CAGR: 38.94% | SUE: 0.07 | # QB: 0
EPS next Quarter (2026-03-31): EPS=0.01 | Chg30d=+0.000 | Revisions Net=+0 | Analysts=2
EPS next Year (2026-12-31): EPS=0.31 | Chg30d=+0.000 | Revisions Net=+0 | Growth EPS=+399.2% | Growth Revenue=+26.0%

Additional Sources for XERS Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle